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pLevodopa has been detected in human milkCaution should be exercised when SINEMET is administered to a nursing woman./ppYou may feel light-headed or dizzy while taking SINEMETThis is because your blood pressure is falling suddenlyStanding up slowlyespecially when you get up from bed or chairswill help your body get used to the change in position and blood pressureIf this problem continues or gets worsetell your doctor./ppYour doctor may want you to gradually reduce the amount of SINEMET you are using before stopping completelyThis may help reduce the possibility of withdrawal symptoms such as muscle stiffnessfever and mental changes./ppAbnormalities in laboratory tests may include elevations of liver function tests such as alkaline phosphataseSGOTASTSGPTALTlactic dehydrogenaseLDHand bilirubinAbnormalities in blood urea nitrogenBUNand positive Coombs test have also been reportedCommonlylevels of blood urea nitrogencreatinineand uric acid are lower during administration of SINEMET than with levodopa./ppLevodopa is a metabolic precursor of dopamine or a compound that participates in the chemical reaction that produces dopaminewhich is able to cross the blood-brain barrier and reach the brainwhere it can be converted to dopamine./p
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