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pCombination treatment with metformin is associated with an increased risk of hypoglycaemia./ppPatients can be transferred directly from other oral hypoglycaemic medicinal products to repaglinideHoweverno exact dosage relationship exists between repaglinide and the other oral hypoglycaemic medicinal productsThe recommended maximum starting dose of patients transferred to repaglinide is 1 mg given before main meals./ppYou may be more likely to have hyperglycemiahigh blood sugarif you are taking repaglinide with other drugs that raise blood sugarsuch as:/ppCo-administration of cimetidinenifedipineoestrogenor simvastatin with repaglinideall CYP3A4 substratesdid not significantly alter the pharmacokinetic parameters of repaglinide./p
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